Pilot Funding Awardees

The Indiana CTSI provides pilot funding to support research projects from individuals and teams in all areas of translational research related to the prevention, diagnosis, and management of human disease.

Help Us Celebrate

View the current list of awardees to see examples of the kinds of projects that the Indiana CTSI has invested in to help improve human health, as well as to showcase innovative and impactful translational research being done across Indiana.

Use the filter on this list to find out what types of projects are funded by a specific mechanism and to learn about potential collaborators working in your field.

2024 – Clinical & Translational Science (CTS)
Bondesson Bolin, Maria Indiana University Bloomington Development of a toxicoproteomic tool for improved risk assessment of environmental pollutants
Das, Arupratan Indiana University School of Medicine Mechanisms for enhancing success of stem cell-based regenerative medicine
Green, Leopold Purdue Drug Delivery across the Blood-Brain Barrier
Henderson, Gregory Purdue University Development of a method to enable pre-clinical studies of acute hypoalbuminemia
Piganelli, Jon Indiana University School of Medicine Soluble Lymphocyte Activationn Gene -3 (s-LAG-3): A Potential Surrogate Marker for Disease Progression and Immunotherapy Success
Prosperi, Jeni Indiana University School of Medicine Biochemical and biological investigations with potential therapeutic connections
Sereno, Anne Purdue Overcoming Process Barriers in Neuroimaging Studies on Age-Related Attentional Deficits
Stephens, Bryan Indiana University Bloomington Translational Support Factors and Barriers in Multidisciplinary Science Teams: Developing Evidence-Based Interventions and Experiment Protocol

2023 – Clinical & Translational Science (CTS)
Greenfield, Edward Indiana University School of Medicine Validation of a 3D Spheroid Platform to Personalize Oncology Drugs
Kolbinger, Fiona Purdue University Prediction and Early Detection of Pancreatic Cancer Using Multimodal Artificial Intelligence
Leung, Yuk Purdue University Improving Drug Discovery Efficiency for Retinal Degeneration by Functional Drug Screening
Lim, Kenneth Indiana University School of Medicine Creating a novel digital platform for capturing Cardiopulmonary Exercise Testing (CPET) data in Indiana
Collaboration in Translational Research (CTR)

2022 – Collaboration in Translational Research (CTR)
Abebe, Ephrem Purdue University OTC Senior Station: A Consumer Facing Technology to Improve Medication Safety for Older Adults
DePaoli-Roach, Anna Indiana University School of Medicine Identification of New Lead Small Molecules for the Treatment of Glycogen Storage Disease Type III; Cori Disease
Holden, Richard Indiana University School of Medicine–Bloomington OTC Senior Station: A Consumer Facing Technology to Improve Medication Safety for Older Adults
Honaker, Sarah Indiana University School of Medicine Sleep, feeding, and obesity risk during infancy in African American and Latinx families
Jin, Xiaoming Indiana University School of Medicine Brain epigenetic mechanism of acupuncture on neuropathic pain
Lee, Jessica Indiana University Indianapolis Addressing Disparities in Autism Spectrum Disorder (ASD) among Burmese Refugee families in Central Indiana
Logrip, Marian / Lukkes, Jodi Indiana University Indianapolis / Indiana University School of Medicine Adolescent social isolation effects on alcohol drinking & neuroadaptations in dorsal raphe-basolateral amygdala circuit
Lu, Tao Indiana University School of Medicine Improving the potency of novel PRMT5 inhibitor with nanocrystal technology to treat pancreatic cancer
Moding, Kameron Purdue University Sleep, feeding, and obesity risk during infancy in African American and Latinx families
Otte, Andrew Purdue University Long-acting ketamine for pain due to bone fracture
Patel, Rita / Gupta, Kunal Indiana University–Bloomington / Indiana University School of Medicine Deep brain stimulation for laryngeal dystonia: from mechanism to optimal application
Taylor, Rich University of Notre Dame Identification of New Lead Small Molecules for the Treatment of Glycogen Storage Disease Type III; Cori Disease
White Fletcher Indiana University School of Medicine Long-acting ketamine for pain due to bone fracture
Yuan, Chongli Purdue University Brain epigenetic mechanism of acupuncture on neuropathic pain
Zhou, Xiang Purdue University Addressing Disparities in Autism Spectrum Disorder (ASD) among Burmese Refugee families in Central Indiana

2021 – Collaboration in Translational Research (CTR)
Ferradal, Silvina Indiana University School of Medicine–Bloomington Early prediction of withdrawal in infants with prenatal opioid exposure using quantitative measurements
Goni Cortes, Joaquin Purdue University Uncovering fingerprints of brain network flexibility in alcohol use disorders
Guo, Feng Indiana University School of Medicine–Bloomington A Tumor-on-a-Chip Platform for Modeling Immuno-Oncology in Prostate Cancer
Han, Bumsoo Purdue University Application of a biomimetic model to assess the effects of perfluoroalkyl substances (PFAS) on pancreatic cancer
Hocevar, Barbara / Kamendulis, Lisa Indiana University School of Medicine–Bloomington Application of a biomimetic model to assess the effects of perfluoroalkyl substances (PFAS) on pancreatic cancer
Kareken, David Indiana University School of Medicine Uncovering fingerprints of brain network flexibility in alcohol use disorders
Lu, Xin University of Notre Dame A Tumor-on-a-Chip Platform for Modeling Immuno-Oncology in Prostate Cancer
O’Sullivan, Thomas D. University of Notre Dame Early prediction of withdrawal in infants with prenatal opioid exposure using quantitative diffuse optical spectroscopy
Raman, Subha / Stewart, Jesse Indiana University School of Medicine / Indiana University Indianapolis Longer-Term Cardiovascular and Psychiatric Consequences of SARS-CoV-2 Infection: Prevalence and Insights into Shared Mechanisms.
Schlader, Zachary / Basile, David Indiana University–Bloomington / Indiana University School of Medicine Heat waves, aging, and the kidneys
Community, Healthcare Delivery & Implementation Science PDT

2023 – Community, Healthcare Delivery & Implementation Science PDT
Halverson, Colin Indiana University School of Medicine Emoji, Ethics, and Professionalism Focus Group Study
Mazurenko, Olena Indiana University Indianapolis Virtual perspective-taking training to reduce pain treatment disparities

2022 – Community, Healthcare Delivery & Implementation Science PDT
Johns, Shelley Indiana University School of Medicine Telephone Acceptance and Commitment Therapy Intervention for Caregivers (TACTICs) of Adults with Alzheimer’s Disease and Related Dementias: Pilot RCT
Vest, Joshua Indiana University Indianapolis Translating existing electronic data into computable social factor phenotypes
Vest, Joshua Indiana University Indianapolis IUCRC Phase 1: Center for Population Health Analytics & Technology (CPHAT)
Concepts to Clinic PDT

2023 – Concepts to Clinic PDT
Brutkiewicz, Randy Indiana University School of Medicine MR1/MAIT cell axis in tau pathology
Plotkin, Lilian Indiana University School of Medicine Use of Novel Mice to Image Apoptotic Osteocytes
Powell, Nicholas Indiana University School of Medicine Discovery of mechanism-related biomarkers of CYP2C19 downregulation in NAFLD
Sheets, Patrick Indiana University School of Medicine Elucidating sex-specific disruption of mPFC circuits in chronic pain states
Yu, Andy Indiana University School of Medicine Function and mechanism of CD1d-mediated neuroinflammation after spinal cord injury

2022 – Concepts to Clinic PDT
Brutkiewicz, Randy Indiana University School of Medicine Modulating Neuroinflammation After Spinal Cord Injury
Callaghan, Tom Indiana University School of Medicine Addressing the Musculoskeletal Phenotype in Hypermobile Ehlers-Danlos Syndrome: Biomarker Pilot Study
Coggan, Andrew Indiana University Indianapolis Kynurenine and NAD+ as Biomarkers of ICU Acquired Weakness in Older Adults
Corson, Tim Indiana University School of Medicine Efficacy studies of SH-11037, a therapy for neovascular eye disease
Gupta, Kunal Indiana University School of Medicine RNA sequencing of the whole dentate gyrus in early temporal lobe epileptogenesis
Hall, Mark Purdue University Cdc14 phosphatase roles in fungal drug resistance and pathogenesis
Hato, Takashi Indiana University School of Medicine Mechanisms of sepsis-induced organ failure
Jackman, Christopher Indiana University School of Medicine Bone effects of anti-CGRP medications for Migraine
Kacena, Melissa Indiana University School of Medicine In vivo SARS-CoV-2 exposure via dental aerosol in a COVID-19 mouse model
Khan, Babar Indiana University School of Medicine Improving sleep in acute respiratory failure ICU survivors
Lasagna-Reeves, Cristian Indiana University School of Medicine The role of Bassoon on pathological tau propagation in Alzheimer’s disease (AD) and other Tauopathies
Lockett, Angelia Indiana University School of Medicine S1P Induces Activation of the Mitochondrial Unfolded Protein Response to Promote Vascular Cell Proliferation in PAH
Maiers, Jessica Indiana University School of Medicine Elucidating the role of ATF6a as a critical pro-fibrogenic transcription factor in Hepatic Stellate Cells
Munoz Ramirez, Braulio Alfredo Indiana University School of Medicine Role of mu-opioid receptor activation on inhibitory transmission in dorsal striatum
Niziolek, Paul Indiana University School of Medicine MRI Determination of Femoral Neck Cortical Porosity in Chronic Kidney Disease Metabolic Bone Disease (CKD-MBD)
Plotkin, Lilian Indiana University School of Medicine Gonadal vs chromosomal sex and osteocytic miR21 in the control of bone mass and strength
Samala, Niharika Indiana University School of Medicine Sarcopenia in NASH Cirrhosis
Tesini Roseguini, Bruno Purdue University Home based leg heat therapy to combat age-related loss of skeletal muscle mass and function
Tran, Taun Indiana University School of Medicine Evaluating the dynamics and function of naturally acquired humoral immune responses to Plasmodium vivax vaccine candidate antigens in a longitudinal study

2020 – Concepts to Clinic PDT
Ballinger, Tarah Indiana University School of Medicine Impact of mechanical signals on bone and muscle composition in early stage breast cancer patients receiving aromatase inhibitors
Lu, Xin University of Notre Dame Generation of HA-tagged PYGO2 CRISPR knock-in mice at Jackson Laboratory
Core Pilot

2024 – Core Pilot
Recipient
Institution
Title
Core(s)
Location(s)
Aryal, Uma Purdue University Role of Promyelocytic Leukemia Nuclear Bodies in Cellular Senescence Proteomics Facility Imaging Facility Purdue University
Hill, Catherine Purdue University Accelerating discovery of next-generation insecticides for mosquito control using Mass Spectrometry Imaging Metabolite Profiling Facility Purdue University
Kirchmaier, Ann Purdue University Genome Integrity Defects in HLRCC Imaging Facility Purdue University
Lee, Hongmi Purdue University Brain mechanisms of real-world information seeking and learning during free web browsing MRI Facility Purdue University
Li, Jianneng University of Notre Dame A novel mechanism of rucaparib reversal enzalutamide resistance in prostate cancer Genomics and Bioinformatics Core Facility Mass Spectrometry and Proteomics Facility University of Notre Dame
Sereno, Anne Purdue University Investigations of semantic maps in the dorsal and ventral cortical visual streams MRI Facility Purdue University
Suter, Daniel Purdue University Light sheet fluorescence microscopy for imaging nervous system development in zebrafish Imaging Facility Purdue University
Tisdale, James Purdue University Development and Validation of a Risk Score for QT Interval Prolongation in Older Adults Regenstrief Data Services Regenstrief Institute

2023 – Core Pilot
Recipient
Institution
Title
Core(s)
Location(s)
Adams, Katrina University of Notre Dame Profiling neural stem and progenitor cells in Multiple Sclerosis Genomics and Bioinformatics Core Facility University of Notre Dame
Adeoye-Olatunde, Omolola Purdue University Evaluating the Impact of a Coach-Led Mobile Health (mHealth) Intervention on Hypertension Management in Nigeria Biostatistics and Health Data Science Core Indiana University School of Medicine
Androphy, Elliot Indiana University School of Medicine Proteomic Analysis of the alpha-COP interactome Center for Proteome Analysis Indiana University School of Medicine
Bidelman, Gavin Indiana University School of Medicine–Bloomington Characterizing the functional role of auditory corticofugal efferent pathways to human hearing using in-vivo multimodal neuroimaging Imaging Research Facility Indiana University–Bloomington
Brault, Jeffrey Indiana University School of Medicine Mitochondrial DNA mutations as a component of skeletal muscle atrophy Center for Medical Genomics Indiana University School of Medicine
Chan, Shing Fai Indiana University School of Medicine Serum Lipidomic Profiling and Lipid Metabolite Biomarker Discovery in Patients with Hemorrhagic Myocardial Infarction Metabolite Profiling Facility Purdue University
Custer, Sara Indiana University School of Medicine Axon-TRAP to survey local translation in mouse motor neurons Center for Medical Genomics Indiana University School of Medicine
Dahl, Richard Indiana University School of Medicine Determining the Contribution of Metabolic Disruption to the Anti-Inflammatory Phenotype of MIRC11-/- Macrophages Metabolite Profiling Facility Purdue University
Dydak, Ulrike Purdue University MRI Evaluation of Molecular Mechanisms of Perfusion and Renal Viability of Ex-Vivo Kidneys to Indicate Transplant Outcomes MRI Facility Purdue University
Gomes, Catia Indiana University School of Medicine Transcriptional profiling of human reactive astrocytes after complement pathway modulation Center for Medical Genomics Indiana University School of Medicine
Graham, Brett Indiana University School of Medicine Determination of the Altered Metabolome at Single Fiber Resolution in a Mouse Model of Mitochondrial Myopathy Metabolite Profiling Facility Purdue University
He, Qiuhong Purdue University Development of methods for simultaneous imaging of glioma markers MRI Facility Purdue University
Huot, Joshua Indiana University School of Medicine Transcriptional profiling of human reactive astrocytes after complement pathway modulation Genome Editing Center Indiana University School of Medicine
Lim, Kenneth Indiana University School of Medicine Development of A Novel a-Klotho Proteomic Assay Center for Proteome Analysis Indiana University School of Medicine
Lu, Tao Indiana University School of Medicine Critical role of novel NF-kB O-GlcNAcylation in pancreatic cancer Preclinical Modeling and Therapeutics Core Indiana University School of Medicine
Mukherjee, Angana University of Notre Dame Genomic Architecture of Unique Artemisinin Resistant Plasmodium falciparum from Bangladesh Genomics and Bioinformatics Core Facility University of Notre Dame
Noinaj, Nicholas Purdue University Structural characterization of novel inhibitors against Neisserial BAM Cryo-EM Facility Purdue University
O’Hagan, Heather Indiana University School of Medicine–Bloomington Elucidating the mechanism by which LSD1, CoREST2, and STAT3 promote enteroendocrine cell differentiation in mucinous colorectal cancer Center for Genomics and Bioinformatics Indiana University–Bloomington
Pelletier, Stephane Indiana University School of Medicine Lipid metabolism defects in SCYL1 deficiency syndrome Metabolite Profiling Facility Purdue University
Schutzman, Linda Indiana University School of Medicine Investigation of cellular adhesion molecules in pulmonary artery thrombosis following blunt thoracic trauma Indiana Center for Biological Microscopy Indiana University School of Medicine
Smith, Brenda Indiana University School of Medicine Profiling Candidate Xenometabolites Altered in Response to Prebiotic and Exercise for Improving Skeletal Health Metabolite Profiling Facility Purdue University
Smith, Gerald Indiana University School of Medicine–Bloomington Neurosteroid Metabolism and Evolution of Sexually Dimorphic Behavior Laboratory for Biological Mass Spectrometry Indiana University–Bloomington
Surowiec, Rachel Indiana University Indianapolis Improving Bone Stress Injury Prediction using Ultrashort Echo Time (UTE) Magnetic Resonance Imaging MRI Facility Purdue University
Tilston-Lunel, Natasha Louise Indiana University School of Medicine Identification of the cellular interacting partners of Oropouche virus non-structural protein NSs Center for Proteome Analysis Indiana University School of Medicine
Tran, Ngoc Tung Indiana University School of Medicine Targeting protein arginine methyltransferase 1 for multiple myeloma treatment In Vivo Therapeutics Core Indiana University School of Medicine
Witczak, Carol Indiana University School of Medicine Synthesis of a glucose photolabeling reagent for the identification of novel glucose transporters in skeletal muscle Chemical Genomics Core Facility Indiana University School of Medicine
Zhao, Bo Indiana University School of Medicine Generation of Knock-in Mice Expressing Fluorescently Tagged RIPOR2 Genome Editing Center Indiana University School of Medicine

2022 – Core Pilot
Recipient
Institution
Title
Core(s)
Location(s)
Conroy, Andrea Indiana University School of Medicine Lipid peroxidation as a modifiable target in severe malaria associated acute kidney injury Proteomics Facility Metabolite Profiling Facility Purdue University
Das, Arupratan Indiana University School of Medicine Investigating glaucoma neuroprotection effect on the visual pathway of mice brain In-Vivo Imaging Core Indiana University School of Medicine
Duffield, Giles University of Notre Dame The impact of Artificial light at night on Aedes aegypti biting behavior: a genomics analysis of the Zika mosquito brain Genomics and Bioinformatics Core Facility University of Notre Dame
Ferdig, Michael University of Notre Dame Optimizing bulk segregant analysis of drug resistance in Plasmodium falciparum Genomics and Bioinformatics Core Facility University of Notre Dame
He, Qiuhong Purdue University Fast Biomarker Imaging for Early Detection of Neoadjuvant Chemotherapy Response in Triple Negative Breast Cancer (TNBC) using pi-SelMQC Methods In-Vivo Imaging Core Indiana University School of Medicine
Henderson, Gregory Purdue University Electron microscopy to assess cellular responses to altered fatty acid trafficking Life Science Microscopy Facility Purdue University
Hetrick, William Indiana University School of Medicine–Bloomington Cerebellar Involvement in Social Cognition Processes in Schizophrenia Imaging Research Facility Indiana University–Bloomington
Hockerman, Gregory Purdue University Characterization of beta cell-specific IRBIT knock out mice Islet and Physiology Core Proteomics Facility Indiana University School of Medicine / Purdue University
Huot, Joshua Indiana University School of Medicine Tumor-derived FGF21 mediates musculoskeletal wasting in colorectal cancer Genome Editing Center Indiana University School of Medicine
Little, Dianne Purdue University Histology of the Humeral Head and Glenoid in Asymptomatic Primary Glenohumeral Osteoarthritis Histology Research Laboratory Purdue University
Luo, Wei Indiana University School of Medicine The regulation of cross-reactivity in germinal center B cell response Center for Medical Genomics Indiana Center for Biological Microscopy Indiana University School of Medicine
Ma, Yao-Ying Indiana University School of Medicine Highly Sensitive MRI to detect age and environmental effects in addiction models In-Vivo Imaging Core Indiana University School of Medicine
Nelson, Rick Indiana University School of Medicine Multiomic Landscape of Human Vestibular Schwannomas Center for Medical Genomics Indiana University School of Medicine
Patzke, Christopher University of Notre Dame Generation and Analysis of Translational Neural Cell Culture Models for Kabuki Syndrome: A Developmental Disorder Causing Intellectual Disability Genomics and Bioinformatics Core Facility University of Notre Dame
Pierchala, Brian Indiana University School of Medicine Identification of the neuronal populations that underly the sense of taste Center for Medical Genomics Indiana University School of Medicine
Tepper, Robert Indiana University School of Medicine Chronic Developmental Hypoxia Suppresses Airway Reactivity Center for Medical Genomics Indiana University School of Medicine
Thompson, William Indiana University Indianapolis Generation of a Transgenic Mouse to Drive/Restore Perlecan Expression Genome Editing Center Indiana University School of Medicine
Tillman, Emma Indiana University School of Medicine Cystic fibrosis transmembrane conductance regulator modulator plasma concentrations and correlation with mental and physical health adverse drug reactions Clinical Pharmacology Analytical Core Indiana University School of Medicine
Vaughan, Kevin University of Notre Dame A Chemical Library Screen for Inhibitors of VRK1 Chemical Genomics Core Facility Purdue University
Weaver, Abigail University of Notre Dame A Deeper Dive into the Biofilm Architecture of Microbes Causing Prosthetic Joint Infection Optical Microscopy Core University of Notre Dame
Yeh, Elizabeth Indiana University School of Medicine Phosphorylation-mediated Regulation of the Rubicon Interactome Center for Proteome Analysis Indiana University School of Medicine

2021 – Core Pilot
Recipient
Institution
Title
Core(s)
Location(s)
Adeoye-Olatunde, Omolola Purdue University Social Determinants of Health and Medication Adherence among Chronically Ill Older Adults in the United States Biostatistics and Health Data Science Core Indiana University School of Medicine
Atwood, Brady Indiana University School of Medicine Proteomic assessment of brain mechanisms underlying sex-specific effects of prenatal methadone exposure on alcohol-related behaviors Center for Proteome Analysis Indiana University School of Medicine
Blazer-Yost, Bonnie Indiana University Indianapolis Characterization and Optimization of Target Compounds to Treat Hydrocephalus Clinical Pharmacology Analytical Core Indiana University School of Medicine
Chang, Leifu Purdue University Mechanisms for inhibition of the Csy complex by anti-CRISPR proteins Cryo-EM Facility Purdue University
Cross, Tzu-Wen Purdue University Link between gut microbiome and brain proteome relevant to Parkinson’s Disease pathology Proteomics Facility Purdue University
Datta, Meenal University of Notre Dame The myeloid “mechanome”: Identifying new treatment targets in glioblastoma Genomics and Bioinformatics Core Facility University of Notre Dame
De Luca, Thomas Indiana University School of Medicine Spatial metabolomics of sepsis-induced kidney injury in the diabetic milieu Metabolite Profiling Facility Purdue University
Ejendal, Karin Purdue University Analysis of the developing proteome in a mouse model of autism spectrum disorder Proteomics Facility Purdue University
Engle, Staci Indiana University Indianapolis Role of hedgehog signaling in energy homeostasis and obesity Center for Proteome Analysis Indiana University School of Medicine
Gangopadhyay, Ishanti Indiana University School of Medicine–Bloomington Word learning mechanisms in bilingual children with Autism Spectrum Disorder: The use of social-pragmatic cues Biostatistics Consulting Center Indiana University–Bloomington
Greenfield, Edward Indiana University School of Medicine Regulation of Macrophage Subsets by Orthopaedic Wear Particles Center for Medical Genomics Indiana University School of Medicine
Hall, Mark Purdue University Proteomic characterization of Cdc14 phosphatases in fungal pathogens Proteomics Facility Purdue University
Howe, Erin University of Notre Dame Identification of the Rab11 interactome Proteomics Facility Purdue University
Huang, Jui-Yen Indiana University School of Medicine–Bloomington Elucidating molecular mechanisms underlying astrocytic FGFRs deficiency-induced neuroinflammation Center for Medical Genomics Indiana University School of Medicine
Hundley, Heather Indiana University School of Medicine Identification of RNA editase-associated modulators of neurodegeneration in a Parkinson disease model Flow Cytometry Core Facility Center for Genomics and Bioinformatics Indiana University–Bloomington
Kacena, Melissa Indiana University School of Medicine Skeletal Changes Following SARS-CoV-2 Infection Histology and Histomorphometry Core Indiana University School of Medicine
Kirchmaier, Ann Purdue University Metabolic Impacts on DNA Repair Center for Medical Genomics Bioinformatics Core Indiana University School of Medicine
Kitase, Yukiko Indiana University School of Medicine Osteocyte Energy Metabolism Under Mechanical Loading Histology and Histomorphometry Core Center for Medical Genomics Indiana University School of Medicine
Kono, Tatsuyoshi Indiana University School of Medicine Visualization of calcium dyshomeostasis in the pathogenesis of diabetes Indiana Center for Biological Microscopy Indiana University School of Medicine
Landreth, Gary Indiana University School of Medicine Therapeutic potential of the niacin receptor (HCAR2) in Alzheimer’s disease Center for Medical Genomics Clinical Pharmacology Analytical Core Bioinformatics Core Indiana University School of Medicine
Lu, Tao Indiana University School of Medicine Characterization of the pharmacokinetic and metabolic properties of novel small molecule PRMT5 inhibitors Clinical Pharmacology Analytical Core Indiana University School of Medicine
Malek, Sarah Purdue University Fourier-transform infrared spectroscopy as a potential diagnostic and predictive biomarker of hip osteoarthritis Biospecimen Management Core Indiana University School of Medicine
McDowell, Mary Ann University of Notre Dame Transcriptomics to Elucidate Methods of Lab-Induced Drug Resistance in Leishmania donovani Genomics and Bioinformatics Core Facility University of Notre Dame
Meyer, Jason Indiana University Indianapolis Proteomic analysis of reactive human astrocytes and derived soluble factors Center for Proteome Analysis Indiana University School of Medicine
O’Hagan, Heather Indiana University School of Medicine–Bloomington Elucidating the role of DNA methylation and chromatin accessibility alterations in platinum-induced gene repression. Center for Genomics and Bioinformatics Indiana University–Bloomington
O’Hagan, Heather Indiana University School of Medicine–Bloomington Elucidating the role of the AKT-EZH2-ß-catenin axis in mediating the transcriptional response to reactive oxygen species in colorectal cancer Center for Genomics and Bioinformatics Indiana University–Bloomington
Pattabiraman, Padmanabhan Indiana University School of Medicine Small Molecule screen to identify novel activators to lower intraocular pressure Chemical Genomics Core Facility Indiana University School of Medicine
Patton, John Indiana University Indianapolis Genetic Stability of Rotavirus Expression Platforms Center for Genomics and Bioinformatics Indiana University–Bloomington
Sajdyk, Tammy Indiana University School of Medicine Evaluation of feasibility of a one-on-one personalized exercise intervention in adolescent and young adult cancer survivors Regenstrief Data Services Regenstrief Institute
Schmidt, Nathan Indiana University School of Medicine Microbiome Impact in the Susceptibility of Red Blood Cell to Malaria Infection Flow Cytometry Resource Facility Indiana University School of Medicine
Schorey, Jeff University of Notre Dame Identifying to the species and subspecies level the non-tuberculosis mycobacteria present in sputum samples obtained from patients in Kenya, Africa Genomics and Bioinformatics Core Facility University of Notre Dame
Shannahan, Jonathan Purdue University Enhanced Resolution of Pulmonary Lipid Alterations via Mass Spectrometry Imaging Metabolite Profiling Facility Purdue University
Subramanian, Ramaswamy Purdue University Structure of Glycosomal Nucleotide Sugar Transporter – A Novel Target Against Disease-Causing Kinetoplastid parasites Cryo-EM Facility Purdue University
Tesini Roseguini, Bruno Purdue University Home-based leg heat therapy to combat age-related loss of skeletal muscle mass and function MRI Facility Purdue University
Wisner, Krista Indiana University School of Medicine–Bloomington A Biobehavioral Process Model of Persecutory Ideation in Early Psychosis Imaging Research Facility Indiana University–Bloomington
Zhang, Li Indiana Biosciences Research Institute To measure islet antigens of type 1 diabetes using a highly multiplexed immunofluorescence assay Indiana Center for Biological Microscopy Indiana University School of Medicine
Zhang, Siyuan University of Notre Dame Dissecting Breast Cancer and Therapy-induced Evolution of Myeloid Lineage by CITEseq Genomics and Bioinformatics Core Facility University of Notre Dame

2020 – Core Pilot
Recipient
Institution
Title
Core(s)
Location(s)
Baker, Lane Indiana University School of Medicine–Bloomington Blood Brain Barrier Model Center for Genomics and Bioinformatics Indiana University–Bloomington
Bruzzaniti, Angela Indiana University Indianapolis Bone-cell specific actions of Kalirin Histology and Histomorphometry Core Indiana University School of Medicine
Chan, Deva Purdue University Multi-Modal Magnetic Resonance Imaging for Functional Assessment of Tissue Repair MRI Facility Purdue University
Clapp, David Indiana University School of Medicine FANCA-Dependent Mitotic Interactions Center for Proteome Analysis Indiana University School of Medicine
Daleke, David Indiana University School of Medicine–Bloomington Toward the cryo-EM structure of a P4-type ATPase monomer, Atp8a1 Electron Microscopy Center Indiana University–Bloomington
Das, Arupratan Indiana University School of Medicine Isolation and Characterization of Mitochondria to Investigate Mitochondrial Optic Neuropathy Center for Proteome Analysis Flow Cytometry Resource Facility Center for Electron Microscopy Indiana University School of Medicine
Demas, Gregory Indiana University School of Medicine–Bloomington Steroidogenic Enzyme Regulation of Aggression Laboratory for Biological Mass Spectrometry Indiana University–Bloomington
Dykhuizen, Emily Purdue University The Role of Polybromo1 (PBRM1) Loss in Checkpoint Inhibition Immunotherapy for Renal Cell Carcinoma Biological Evaluation Purdue University
Elmendorf, Jeffrey Indiana University School of Medicine Imaging skeletal muscle insulin resistance in live mice Indiana Center for Biological Microscopy Indiana University School of Medicine
Fishel, Melissa Indiana University School of Medicine Pre-clinical pilot study to evaluate non-cytotoxic epigenetic therapy for pancreatic cancer In Vivo Therapeutics Core Indiana University School of Medicine
Gao, Ming Indiana University School of Medicine–Northwest-Gary Analysis of RNA Helicase Me31B and Its Interacting RNAs by RNA sequencing Center for Genomics and Bioinformatics Indiana University–Bloomington
Gavin, Tim Purdue University Aging and skeletal muscle exosome miRNA-seq Center for Medical Genomics Bioinformatics Core Indiana University School of Medicine
Hoang, Quyen Indiana University School of Medicine High-throughput chemical screening against the Parkinson’s disease-associated protein LRRK2 Chemical Genomics Core Facility Indiana University School of Medicine
Kalinovsky, Anna Indiana University School of Medicine–Bloomington Effects of Phytocannabinoids on Cerebellar Axon Growth and Fasciculation Light Microscopy Imaging Center Indiana University–Bloomington
Lu, Hui-Chen Indiana University School of Medicine–Bloomington Elucidate NMNAT2’s roles in brain health with longitudinal PET-MRI In-Vivo Imaging Core Indiana University School of Medicine
Lu, Kun-Han Purdue University 4D MRI assessment of gastric motility after selective vagotomies in rats MRI Facility Purdue University
Lu, Xin University of Notre Dame Go Keto: A New Paradigm to Enhance Cancer Immunotherapy Freimann Life Sciences Center University of Notre Dame
Naidu, Samisubbu Indiana University School of Medicine Induction of Mitophagy in Endothelial Cells from Pulmonary Arterial Hypertension Center for Electron Microscopy Indiana University School of Medicine
Newton, Irene Indiana University School of Medicine–Bloomington Understanding Bifidobacterium’s Presence in Infants Using Novel Sequencing Center for Genomics and Bioinformatics Indiana University–Bloomington
Noinaj, Nicholas Purdue University Unraveling zinc piracy in Neisseria Cryo-EM Facility Purdue University
Pestilli, Franco Indiana University School of Medicine–Bloomington Development and Validation of a Visual Field Mapping Protocol in Children Imaging Research Facility Indiana University–Bloomington
Snyder, Margie Purdue University Feasibility Pilot of Linking Patient-Reported Outcomes Collected in Community Pharmacies with Electronic Health Record Data Regenstrief Data Services Regenstrief Institute
Takagi, Yuichiro Indiana University School of Medicine Structure of the Mediator complex of transcription regulation Cryo-EM Facility Purdue University
Tang, Pei-Ciao Indiana University School of Medicine Regulation of Early Ectodermal Development Center for Medical Genomics Indiana University School of Medicine
Thompson, William Indiana University Indianapolis Generation of a Novel Mouse Model to Restore/Overexpress the a2d1 VSCC Subunit Genome Editing Center Indiana University School of Medicine
Tisdale, James Purdue University Risk of Drug-Induced QT Interval Prolongation and Associated Proarrhythmia in Patients with Heart Failure with Preserved Ejection Fraction Regenstrief Data Services Regenstrief Institute
Walczak, Claire Indiana University School of Medicine–Bloomington Single Cell Seq to Identify Heterogeneity in Polyploid Cells Center for Genomics and Bioinformatics Indiana University–Bloomington
Warden, Stuart Indiana University Indianapolis Impact of physical activity on hip bone and cartilage health In Vivo Therapeutics Core Indiana University School of Medicine
Yang, Danzhou Purdue University Structure Study of Nucleolin-MYC promoter DNA G-quadruplex Complex Cryo-EM Facility Purdue University
Ziarek, Joshua Indiana University School of Medicine–Bloomington Molecular mechanisms of arrestin activation NMR Facility Indiana University–Bloomington
Drug Development to Commercialization PDT

2023 – Drug Development to Commercialization PDT
Blazer-Yost, Bonnie Indiana University Indianapolis Development of Drugs to Treat Hydrocephalus

2022 – Drug Development to Commercialization PDT
Alves, Nathan Indiana University School of Medicine Nanoparticle delivery of clot digesting enzymes
Corson, Tim Indiana University School of Medicine Efficacy studies of SH-11037, a therapy for neovascular eye disease
Gaston, Benjamin Indiana University School of Medicine Optate, an airway anti-inflammatory drug with antiviral properties
Johnson, Steve Indiana University School of Medicine Developing GroEL inhibitors for combatting methicillin-resistant Staphylococcus aureus (MRSA)
Grant Linking Universitywide Expertise (GLUE)

2023 – Grant Linking Universitywide Expertise (GLUE)
Hajos, Norbert / Wang, Nian Indiana University–Bloomington / Indiana University School of Medicine Brain-wide changes in connectome upon amygdala-driven epileptic seizures
Mackie, Ken Indiana University School of Medicine Role of CB2 receptors in the treatment of atopic and allergic contact dermatitis

2022 – Grant Linking Universitywide Expertise (GLUE)
Mitra, Anirban / Zhang, Chi Indiana University–Bloomington / Indiana University School of Medicine Regulation of ovarian cancer metastatic colonization through clonal selection
Human Health & Biomedical Technology PDT

2024 – Human Health & Biomedical Technology PDT
Casey, Theresa/Beckett, Linda Purdue University Impact of Saturated and Unsaturated Fatty Acids on Kidney Fluxomics and Proteomics
LaCount, Douglas Purdue University Molecular basis for DENV multiple serotype co-infections
Pires dos Santos, Andrea Purdue University Evaluation of the contribution of genital ureaplasmas in the etiopathogenesis of miscarriage in Brazilian women
South, Susan Purdue University Differences in Risk for Alzheimer’s Disease: Daily Measures of Mood, Cognition, and Social Engagement

2023 – Human Health & Biomedical Technology PDT
Byrn, Stephen / Clase, Kari Purdue University A platform for enhancing the potency of drugs
Chaudhry, Faria Purdue University Evaluating the impact of a community health worker for diabetes management in selfemployed women in India
Fernandes, Igor Purdue University Mapping the central and peripheral causes of autonomic dysfunction in pulmonary arterial hypertension
Koss, Wendy Purdue University Sex differences in the timing and severity of cognitive deficits and pathology using the 3xTg mouse model of Alzheimer’s disease
Metskas, Lauren / Kuhn, Richard Purdue University Fluorescent labeling of bunyavirus for in vivo assembly studies

2022 – Human Health & Biomedical Technology PDT
Bowman, Aaron / Rochet, Jean-Christophe Purdue University Sex Differences in Neuropathology and Excitotoxicity in a Stem Cell Model of Alzheimer’s Disease
Chaudhry, Faria Purdue University Evaluating the impact of a community health worker for diabetes management in selfemployed
Das, Chittaranjan Purdue University Identification of host targets of a bacterial effector with a novel deADP-ribosylase activity
Running, Cordelia / Gletsu Miller, Nana Purdue University Trading Sugar for Sparkle

2021 – Human Health & Biomedical Technology PDT
Bhunia, Arun Purdue University Fate of LAP as Excipient during Drug Delivery
Cooks, Robert Graham Purdue University Walk-up system to sample breath, perform MS and output Y/N respiratory infection status
DeMaria, Andrea Purdue University Improving Overall Quality of Life for Uterine Fibroid Patients
Hu, Chang-Deng Purdue University Cryo-EM Structural Analysis of PRMT5 in Complex with pINIn
Kimbrough, Adam Purdue University Exploring sex differences in how the brain responds to oxycodone use
Yang, Yang Purdue University The role of oxytocin in a mouse model of Scn2a deficiency

2020 – Human Health & Biomedical Technology PDT
Cross, Tzu-Wen Purdue University Gut microbiome and estrogen receptor signaling: potential implication on gastrointestinal-related disease
Foti, Daniel Purdue University Developing a novel protocol for home-based electroencephalography assessment of families affected by Angelman syndrome
Roseguini, Bruno Purdue University Heat therapy to improve skeletal muscle function in a model of Duchenne muscular dystrophy
Human Health & Biomedical Technology PDT / Women’s Global Health Institute

2022 – Human Health & Biomedical Technology PDT / Women’s Global Health Institute
LaRoche, Kathryn Purdue University Exploring Patient Experiences with Miscarriage Care in Indiana in the Midst of a Shifting Regulatory Environment
Main, Russell / Figueriredo, Marxa Purdue University Maximizing peak bone mass: Interactions among genetics and mechanical loading
Large Collaborative Grant

2023 – Large Collaborative Grant
Breathett, Khalid Indiana University School of Medicine Changing Generational Trajectory of CVD with the Adult Children and Grandchildren of WHI (TRAJECTORY Study)
Kacena, Melissa Indiana University School of Medicine Integrating clinical and preclinical data to identify novel therapeutics for chronic fracture pain
Lamb, Bruce Indiana University School of Medicine Genetic Alterations in Microglia and AD
Mosley, Amber Indiana University School of Medicine Thermal proteome profiling technologies to provide a mechanistic understanding of human genetic and epigenetic based diseases
MedTech Commercialization PDT

2023 – MedTech Commercialization PDT
Aguirre, Milton Purdue University A.I.R Pen Pitch
Bacallao, Bob Indiana University School of Medicine Mathematical Modeling of Hydrodynamic Fluid Pulses
Lippman, David Indiana University School of Medicine ‘Walqer’ Walking Assistive Device

2022 – MedTech Commercialization PDT
Garcia, Kara/Myung, Nosay Indiana University School of Medicine/University Notre Dame Smart Insulin Leak Detector
Pediatrics PDT

2023 – Pediatrics PDT
Kao, Shih-Chun Purdue University Supporting high-intensity interval training with mindfulness for enhancing childhood executive function
Sharp, Sacha Indiana University School of Medicine Improving Access to Quality Healthcare for Black Birthing People

2022 – Pediatrics PDT
Moding, Kameron Purdue University Objective remote assessments of family sleep and stress
Rodriguiz, Gabriela Indiana University School of Medicine Characterizing Usual Care for Youth with Disruptive Behavior Disorders in Indiana Community Mental Health Centers
Williams, Amy Indiana University School of Medicine Examination of mechanisms contributing to impact of insomnia on chronic pain risk and outcomes in pediatric patients

2021 – Pediatrics PDT
Aguilar, R. Claudio Purdue University Evaluating therapeutic strategies against Lowe syndrome
Postdoc Challenge

2024 – Postdoc Challenge
Recipient
Institution
Title
Core(s)
Location(s)
Andolino, Chaylen Purdue University Characterizing the post-translational modification signatures of metastatic breast cancer cytoplasmic lipid droplets Proteomics Facility Purdue University
Kayode, Tolulope University of Notre Dame A Novel Multiplexed PCR Amplicon Sequencing for Genomic Characterization of Drug Resistance Genes in Plasmodium falciparum Genomics and Bioinformatics Core Facility University of Notre Dame
Thach, Trung Purdue University Mechanistic insights of selective targeting P2X3 receptor by camlipixant Cryo-EM Facility Purdue University

2023 – Postdoc Challenge
Recipient
Institution
Title
Core(s)
Location(s)
Dutta, Sayanta Indiana University School of Medicine Restoration of mitochondrial homeostasis for glaucoma neuroprotection Indiana University School of Medicine Center for Electron Microscopy Indiana University School of Medicine
Ekpruke, Carolyn Indiana University School of Medicine–Bloomington Assessing sex differences in the impact of a ketogenic diet on airway inflammatory cell response in allergen-challenged mice Flow Cytometry Core Facility Indiana University–Bloomington
Sohal, Ikjot Singh Purdue University Classification of human lung tumor specimens based on immune contexture Biospecimen Collection and Banking Core Histology Research Laboratory Indiana University School of Medicine / Purdue University
Souza, Rodolpho Ornitz Oliveira Indiana University School of Medicine Uncovering the role of Myosin A in Toxoplasma gondii mitochondrial biology by live imaging Indiana Center for Biological Microscopy Indiana University School of Medicine
Yu, Tao Indiana University School of Medicine Targeting Glutamine-Glutamate-Glutathione Axis Potentiates Immune Checkpoint Blockade Therapy in Colorectal Cancer Center for Medical Genomics Indiana University School of Medicine

2022 – Postdoc Challenge
Recipient
Institution
Title
Core(s)
Location(s)
Ahn, Taeyong Indiana University School of Medicine The use of nano‐liquid chromatography (LC‐MS) mass spectrometry for the identification of potential protein biomarker candidates related to an anterior cruciate ligament (ACL) injury Center for Proteome Analysis Indiana University School of Medicine
Ahn, Taeyong Indiana University School of Medicine The use of nano‐liquid chromatography (LC‐MS) mass spectrometry for the identification of potential protein biomarker candidates related to an anterior cruciate ligament (ACL) injury Center for Proteome Analysis Indiana University School of Medicine
Barboi, Cristina Indiana University Indianapolis Outcome analysis of intraoperative therapeutic interventions relative to the risk associated with progressive hypotension Regenstrief Data Services Regenstrief Institute
Barboi, Cristina Indiana University Indianapolis Outcome analysis of intraoperative therapeutic interventions relative to the risk associated with progressive hypotension Regenstrief Data Services Regenstrief Institute
Burke, Andrew Indiana University School of Medicine Contribution of social circuits to social familiarity-induced anxiolysis Behavioral Phenotyping Core Indiana University School of Medicine
Burke, Andrew Indiana University School of Medicine Contribution of social circuits to social familiarity-induced anxiolysis Behavioral Phenotyping Core Indiana University School of Medicine
Dou, Xiaozheng University of Notre Dame Structure-based drug design and investigation of cruentaren A analogs Magnetic Resonance Research Center Mass spectrometry and Proteomics Facility University of Notre Dame
Gampala, Silpa Indiana University School of Medicine Deciphering the effects of Ref‐1 redox inhibition on pancreatic cancer metabolism using non‐targeted global metabolomic profiling Metabolite Profiling Facility Purdue University
Gampala, Silpa Indiana University School of Medicine Deciphering the effects of Ref‐1 redox inhibition on pancreatic cancer metabolism using non‐targeted global metabolomic profiling Metabolite Profiling Facility Purdue University
Iyer, Shalini Purdue University Using mass spectrometry to characterize Ub‐related bacterial effectors from Legionella pneumophila Proteomics Facility Purdue University
Liffner, Benjamin Indiana University School of Medicine Proximal labelling of a kinase to identify proteins involved in mitosis of malaria parasites Center for Proteome Analysis Indiana University School of Medicine
Liffner, Benjamin Indiana University School of Medicine Proximal labelling of a kinase to identify proteins involved in mitosis of malaria parasites Center for Proteome Analysis Indiana University School of Medicine
Ma, Jing Indiana University School of Medicine Characterization of neutrophils-released EV-miRNA cargo in alcoholic hepatitis patients Center for Medical Genomics Indiana University School of Medicine
Ma, Jing Indiana University School of Medicine Characterization of neutrophils-released EV-miRNA cargo in alcoholic hepatitis patients Center for Medical Genomics Indiana University School of Medicine
Menon, Aishwarya Vijayan Purdue University Wound closure ability of a bio‐based tissue sealant Histology Research Laboratory Pre-Clinical Research Laboratory Purdue University

2021 – Postdoc Challenge
Recipient
Institution
Title
Core(s)
Location(s)
Chen, Xiaoling Purdue University Optogenetic method for synaptic weight mapping Bindley Bioscience Center Purdue University
Gomes, Catia Indiana University School of Medicine High-throughput screening to identify compounds able to block Glaucomatous Retinal Ganglion Cell degeneration Chemical Genomics Core Facility Indiana University School of Medicine
Huot, Joshua Indiana University School of Medicine Mediator of Musculoskeletal Deficits in Cancer Cachexia Genome Editing Center Indiana University School of Medicine
Reyes Fernandez, Perla Indiana University Indianapolis Regulation of Bone Mechanosensation via Proteoglycan-Based Matrix Tethers Histology and Histomorphometry Core Indiana University School of Medicine
Wright, Christian Indiana University Indianapolis Differential Expression Responses of Osteocytes to Mechanical Loading Following Knockout of the a2d1 Voltage Sensitive Calcium Channel Subunit Following Knockout of the α2δ1 Voltage Sensitive Calcium Channel Subunit Center for Medical Genomics Indiana University School of Medicine
Yen, Yu-Chen Purdue University Cryo-EM structure of adenylyl cyclase 5 in complex with Gβγ Cryo-EM Facility Purdue University
Zuilkoski, Caitlin Indiana University School of Medicine–Bloomington Elucidating the Role of Autophagy in Meiotic Progression Laboratory for Biological Mass Spectrometry Light Microscopy Imaging Center Indiana University–Bloomington
Structural and Social Determinants of Health PDT

2023 – Structural and Social Determinants of Health PDT
Shi, Yiyu University of Notre Dame Promoting Fairness in AI-Enabled Healthcare through Unsupervised Federated Learning: A Pilot Study

2022 – Structural and Social Determinants of Health PDT
Simon, Kosali / Gupta, Sumedha Indiana University–Bloomington / Indiana University Indianapolis Policy, economic and social determinants of health in Medicare populations
Translational Population Health (TPH)

2023 – Translational Population Health (TPH)
Capone, Drew Indiana University School of Medicine–Bloomington Baseline evaluation of a city-wide sanitation intervention in Quelimane, Mozambique
Del Rio, Michelle Indiana University School of Medicine–Bloomington A community-engaged intervention for reducing lead exposure in a high-risk population
Pickett. Andrew Indiana University School of Medicine–Bloomington Characterizing Social Network Support for Physical Activity among Sexual and Gender Minority (SGM) Caregivers of People Living with Alzheimer’s Disease (AD) and Related Dementias (AD/ADRD)

2022 – Translational Population Health (TPH)
Jordan, Evan / Johns, Shelley Indiana University–Bloomington / Indiana University School of Medicine A just in time mobile stress intervention for cancer survivors